I have this weird theory , like in the first episode of the anime sensi said this about Reiko "she was a beautiful human " and also in someepisode forgot hino tell sensi when he turnes small cause someone cursed natsume anyway "you went that far for her to like you" it just says that meybe just maybe that Madara actually loved Reiko and he could be Natsume grandfather wich will be epic and explain why natsume have a yukai eyesI and this is how it goes "Madara is Natsume grandad and he himself doens't know that and he though she had her baby with human while it was his own ! mmm weird anyway I'll pray to god that this is true like I would really love it to be this way please god make it real lol